Sinead Delany-Moretlwe, MBBCh PhD DTM&H is and Director: Research at Wits RHI Professor of Global Health and Infectious Diseases at the University of the Witwatersrand, Johannesburg. Her research interests span the intersections between sexual and reproductive health (SRH) and infectious diseases, particularly in adolescent girls and young women (AGYW). She has been an investigator on several phase III trials of new HIV prevention technologies and led the landmark trial for cabotegravir as injectable PrEP for women. She has also led several implementation studies to optimize oral PrEP use in adolescent girls and young women (AGYW) in eastern and Southern Africa. She has conducted studies to evaluate HPV screening and vaccination approaches for populations living with HIV, as well as studies of novel treatments and vaccines for gonorrhoea. She is an advisor to the South African National Department of Health PrEP technical working group and serves on several WHO and other advisory committees, including PDVAC, the WHO HIV, Hepatitis and Sexually Transmitted Infectious Scientific and Technical Advisory Committee and co-chairs the WHO HHS pregnancy and breastfeeding therapeutics working group.